Ascaris-specific IgE and allergic sensitization in a cohort of school children in the former East Germany
S Dold, J Heinrich, HE Wichmann, M Wjst - Journal of Allergy and Clinical …, 1998 - Elsevier
Background: Helminthic infections induce an IL-4–dependent polyclonal stimulation of IgE
synthetization. It is still unclear, however, what role helminths play in allergic sensitization.
Objective: We sought to determine the relationship between Ascaris-specific IgE and allergic
sensitization in a nontropical country. Methods: In 2 consecutive cross-sectional surveys in
1992-1993 and 1995-1996, data from school entrants (age range, 5 to 7 years), third
graders (age range, 8 to 10 years), and sixth graders (age range, 11 to 14 years) were …
synthetization. It is still unclear, however, what role helminths play in allergic sensitization.
Objective: We sought to determine the relationship between Ascaris-specific IgE and allergic
sensitization in a nontropical country. Methods: In 2 consecutive cross-sectional surveys in
1992-1993 and 1995-1996, data from school entrants (age range, 5 to 7 years), third
graders (age range, 8 to 10 years), and sixth graders (age range, 11 to 14 years) were …
