The panniculitides represent a group of heterogeneous inflammatory diseases that involve
the subcutaneous fat. The specific diagnosis of these diseases requires histopathologic
study because different panniculitides usually show the same clinical appearance, which
consists of subcutaneous erythematous nodules on the lower extremities. However, the
histopathologic study of panniculitis is difficult because of an inadequate clinicopathologic
correlation, and the changing evolutionary nature of the lesions means that biopsy …